To speak up for what you believe in and affect change at any level of government—local, state, or national—is one of our country’s foundational principles. Participation takes various forms, from voting to rallying support for a variety of issues and bringing them to the attention of decision-makers all the way to campaigning. No matter how one chooses to participate, the driving factor is the desire to make a difference. There are a number of efforts currently under way to protect the interests of O&P professionals and the patients they serve. There seems to be an increasing number of patients with amputation who are spearheading efforts to move legislation forward, particularly in the O&P arena. The O&P EDGE talked with four people who are doing just that.