Tailoring Treatment Across the Gamut of PFFD Presentation
Betta Ferrendelli
May 1, 2026
Todd DeWees, MHA, CPO, manager, Shriners Hospitals for Children, Oregon, recently treated two young boys with proximal femoral focal deficiency (PFFD), a rare congenital genetic defect in which the femur is abnormally short and underdeveloped. Because PFFD presentation ranges from a slight leg length discrepancy to the near-complete absence of a femur, there are a variety of solutions that are generally initiated in childhood depending on the severity of the condition, including rotationplasty, a Symes amputation, and prosthetic or orthotic interventions.
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