In the provision of prosthetic care for patients with lower-limb amputation, there are certain characteristics that are immediately apparent to treating professionals. Limb length, muscle strength, painful neuromas, and marked limitations in joint ranges are just some of the factors that we take into consideration as we develop our treatment plans and help our patients prepare for the life challenges following lower-limb amputation. Other factors are less apparent and may escape our immediate recognition. Among these is the phenomenon of decreased bone density. Several articles in the recent literature elucidate the prevalence of decreased bone density in this patient population. The impact that decreased bone density has on such things as fracture risk, pain, and activity levels are not as well understood but have also received some scrutiny. The purpose of this article is to bring to light some of these findings and help practitioners appreciate the significance of bone density in the well-being of their patients.