Many O&P practitioners are directly involved in multi-specialty teams at wound care centers and diabetic clinics. Healing chronic wounds takes time, patience, skill, and a good deal of cooperation. The patients often present with complicating medical histories such as co-existing medical conditions, or prescription drugs that interfere with healing. They may also have a poor quality of life and display symptoms of depression. Against this backdrop, the team must decide the best approach to dressing, off-loading, and closing open wounds.